A imagem sugestiva "retorno do outro" ajuda a indicar o modo como a alteridade interpela no actual contexto de globalização. Esse "outro", o grande ausente da maior parte da história da filosofia ocidental, aparece com força renovada (ou, pelo menos, resiste aos embates da homo-geneização) frente à lógica económica, política e cultural, que pretende anulá-lo na imposição uniforme de um estilo de vida. O seu "retorno" abre possibilidades em várias perspectivas. Aqui apenas esboçamos o que significou este "retorno do outro" (...) na irrupção do pensamento intersubjectivo, bem como as possibilidades que abre para a relação intercultural. The suggestive image, "turn to the other", gives an indication of how alterity challenges the current context of globalisation- This "other" is the great absent in the greater part of the history of Western philosophy. It appears with renovated strength (or at least resists the pressures of homogenisation) in the face of the economic, political, and cultural logic that seeks to annul it through the uniform imposition of a given lifestyle. Its return opens possibilities of varying kinds. Here we wish only to sketch the meaning of this "turn to the other" in the irruption of the inter-subjective thought and possibilities it opens for intercultural relations. (shrink)

Epigenetic and transcriptional variability contribute to the vast diversity of cellular and organismal phenotypes and are key in human health and disease. In this review, we describe different types, sources, and determinants of epigenetic and transcriptional variability, enabling cells and organisms to adapt and evolve to a changing environment. We highlight the latest research and hypotheses on how chromatin structure and the epigenome influence gene expression variability. Further, we provide an overview of challenges in the analysis of biological variability. An (...) improved understanding of the molecular mechanisms underlying epigenetic and transcriptional variability, at both the intra- and inter-individual level, provides great opportunity for disease prevention, better therapeutic approaches, and personalized medicine. Epigenetic and transcriptional variability mediate phenotypic plasticity, enabling adaptation to changing environments. In this review, we describe the sources of inter- and intra-individual variability and discuss epigenetic regulators of gene expression variability, including DNA methylation and chromatin structure. Understanding these molecular mechanisms will improve therapeutic approaches and personalized medicine. (shrink)

Este trabajo se centra en cómo en la España de la segunda mitad del siglo XVIII con motivo de la reforma de los estudios teológicos tanto en los Seminarios –necesaria para la mejora de la formación de uno de los principales agentes del propugnado y urgente cambio religioso– como en las Universidades –en las que se quería sustituir la influencia jesuítica por otra más de acorde con las ideas regalistas– se impulsó la creación de las cátedras De locis theologicis, muchas (...) de las cuales debían seguir el tratado de Melchor Cano y otras seguir a otros tratadistas, pero teniendo presente en sus explicaciones la docta obra de Melchor Cano. También se estudiará en la reforma del Plan de Estudios de la Orden de Frailes Predicadores, así como el rechazo que de todo ello tuvo el importante ilustrado valenciano Gregorio Mayans y Ciscar. The work is about how in the Spain of the second half of the 18th century owing to the theological studies reform as much in Seminaries-necessary to the education improvement of one of the main agents of the proposed and urgent religious change-as in Universities-in which it was wanted to substitute the Jesuitical influence for another more appropriate to the regalist ideas– the creation of the Locis theologicis chairs, many of which had to follow Melchor Cano’s treatise, and other chairs had to follow other authors, was promoted; but bearing in mind in their explanations Melchior Cano’s erudite work. Such treatise will also be studied in the reform of the Order of Preacher’ curriculum, as well as the rejection of all that by the important learned Gregorio Mayans y Ciscar, native of Valencia. (shrink)

Este trabajo se centra en cómo en la España de la segunda mitad del siglo XVIII con motivo de la reforma de los estudios teológicos tanto en los Seminarios –necesaria para la mejora de la formación de uno de los principales agentes del propugnado y urgente cambio religioso– como en las Universidades –en las que se quería sustituir la influencia jesuítica por otra más de acorde con las ideas regalistas– se impulsó la creación de las cátedras De locis theologicis, muchas (...) de las cuales debían seguir el tratado de Melchor Cano y otras seguir a otros tratadistas, pero teniendo presente en sus explicaciones la docta obra de Melchor Cano. También se estudiará en la reforma del Plan de Estudios de la Orden de Frailes Predicadores, así como el rechazo que de todo ello tuvo el importante ilustrado valenciano Gregorio Mayans y Ciscar. The work is about how in the Spain of the second half of the 18th century owing to the theological studies reform as much in Seminaries-necessary to the education improvement of one of the main agents of the proposed and urgent religious change-as in Universities-in which it was wanted to substitute the Jesuitical influence for another more appropriate to the regalist ideas– the creation of the Locis theologicis chairs, many of which had to follow Melchor Cano’s treatise, and other chairs had to follow other authors, was promoted; but bearing in mind in their explanations Melchior Cano’s erudite work. Such treatise will also be studied in the reform of the Order of Preacher’ curriculum, as well as the rejection of all that by the important learned Gregorio Mayans y Ciscar, native of Valencia. (shrink)

The American Institute of certified public accountants (AICPA) has promulgated a Code of Professional Conduct , which has served as the primary ethical standard for public accountants in the United States for more than 20 years. It is now out of date and needs to be replaced with a code of ethics. Just as U.S. generally accepted accounting principles are being migrated toward “principles-based accounting” as part of a convergence with international financial reporting standards, a similar process needs to occur (...) with ethics. This article organizes the primary rules of the AICPA Code around five essential virtues: objectivity, integrity, inquisitiveness, loyalty, and trustworthiness. These virtues correspond to the general principles set forth in the Code of Ethics for Professional Accountants of the International Federation of Accountants (IFAC). From this virtue ethics perspective, various rules of the AICPA Code are critiqued as being inadequate at best, and poorly crafted at worst. The article concludes with the proposition that principles-based ethics serves the profession and the financial reporting process better than the current rules-based approach. (shrink)

Many philosophers hold there are genuine cases of culpable ignorance. This paper argues that there are conditions that can render knowledge epistemically culpable too. First, we contrast culpable ignorance with morally culpable knowledge. Second, we examine the nature of epistemically culpable knowledge using a key example. We then highlight empirical support for the claim that there are real-world conditions that make epistemically culpable knowledge possible. Next, we survey three kinds of epistemic culpability fostered by culpable knowledge. Finally, we address the (...) benefits objection and argue that it fails. (shrink)

A proposta do presente trabalho é analisar desde uma perspectiva antropológica a decisão vocacional entre seminaristas catarinenses. O trabalho de campo através da “objetivação participante” foi desenvolvido no Seminário Filosófico de Santa Catarina, e ampliado para ex-seminaristas, estagiários e padres. Analisando discursos e práticas foi possível perceber como que o despertar da vocação e as decisões implicadas na caminhada vocacional estão relacionados às condições históricas, econômicas e sociais. O primeiro capítulo resgata a história da implantação das dioceses e seminários no (...) Brasil, especificamente em Santa Catarina, possibilitando perceber como que a estrutura da Igreja Católica, em diálogo com as estruturas sociais, condiciona determinados tipos de recrutamento e de representações sobre a vocação sacerdotal. Considerando a multiplicação no número de padres nas últimas três décadas, buscou-se compreender algumas estratégias da Igreja para manter e reproduzir o corpo clerical, principalmente em relação ao papel da família, dos padres e dos coroinhas no processo do despertar e do recrutamento para o seminário. O segundo capítulo explora como aspectos econômicos estão presentes durante o processo de formação dos seminaristas destacando a importância da família, paróquias, comunidades e madrinhas para manter financeiramente o candidato ao sacerdócio. A análise indica como que estes jovens se envolvem num sistema de trocas para manutenção financeira, aonde a dialética de “dar, receber e retribuir” é fundamental para a decisão na caminhada vocacional. Por fim, o terceiro capítulo expõe como a experiência religiosa do sujeito subjaz às representações da vocação e possibilitam compreender a relação entre estruturas postas e a capacidade inventiva dos sujeitos envolvidos no processo de inculcação da vocação. (shrink)

In this essay, I argue that we are merely biological organisms. This view (animalism) explains everyday practices like watching ourselves in the mirror. The claim that we are psychological in nature cannot explain something as trivial as watching ourselves in the mirror. Thus, we should accept animalism.

Sceptical theism is supposed, by a number of philosophers, to undercut the evidential basis for the evidential problem of evil. In this paper, I argue that even ifsceptical theism succeeds, its success comes with a hefty epistemic price: it threatens to undermine a good deal of what we supposedly know. Call this the problem of epistemic evil. Thus, sceptical theism has a costly philosophical price of admission. In light of this, it seems that the evidential problem of evil is harder (...) to dislodge than it might have initially seemed; i.e. with sceptical theism, we trade the evidential problem of evil for the problem of epistemic evil. (shrink)

The purpose of this research is the analysis of a specific cultural and political tension, through two decisive concepts: imagocracy and imagomaquia. Our aim is to define the political battlefield in the arena of audiovisual communication. In the case of Latin America, we have identified two significant moments, in which the popular audiovisual strategies had crucial importance. Our material of research has been both the New Latin American Cinema and the sociology of the decolonial image. We have studied them in (...) depth in order to define the effectiveness of popular audiovisual strategies as nuclei of creation and aesthetic-political resistance, which opposes the hegemonic audiovisual order. (shrink)

En los últimos años, el filósofo surcoreano radicado en Alemania, Byung-Chul Han, viene marcando nuevos derroteros para la reflexión filosófica usando el potencial teórico que surge de la comprensión de las nuevas realidades sociales, políticas y económicas, que marcan esta época de evolución neoliberal y de desarrollo tecnológico, en el contexto de la cuarta Revolución Industrial. Así, temas como la transformación de la biopolítica en psicopolítica se convierten en un punto muy relevante para el análisis de las sociedades actuales y (...) sus derivas. Con este trasfondo de pensamiento, el presente artículo tiene por objetivo sumergirseen las argumentaciones de Han, explorando el papel crucial que desempeñan las emociones en las sociedades del rendimiento, del cansancio y de la infocracia, acudiendo a la metáfora de la “rueda del hámster” como imagen evocadora de las dinámicas de las sociedades actuales. De esta forma, se presenta una perspectiva innovadora de la complejidad del siglo XXI, al adentrarnos en determinados matices del pensamiento de Han, en conexión con la realidad palpable de las emociones, que actúan como el combustible que impulsa a cada individuo en su propia “rueda existencial”. Esta articulación con las experiencias emocionales contribuyede manera significativa a las discusiones contemporáneas acerca de la naturaleza humana en contextos de innovación tecnológica. (shrink)

Assisted Reproductive Technologies, as a solution to the issues of human infertility, have been developed since the mid-twentieth century. The development of these techniques, their progress and results have occurred simultaneously with two events related to ART: the establishment of new rights that have contributed to their endorsement, and the birth of bioethics that have allowed the recognition of their limits. The cultural change due to the coming of ART is characterized by three topics that are discussed in this article (...) and which are all included in the so-called gender ideology: the concept of woman and the control of her body, kinship and parentage, and the idea of autonomy. Some considerations on these topics are presented as well as some alternatives to ART, which include learning to redirect their work based on criteria pointed out by bioethical reflection. Such criteria reveal the profound meaning of preserving the dignity of every single person within a true human framework. (shrink)

A popular tactic for defending abortion rights is appealing to self-ownership: since I own my body, a foetus has the right to occupy it only if I allow it. One cannot be forced to bring a pregnancy to term because that would violate one's self-ownership. The same logic applies to speech: we have freedom of speech because we produce speech using the bodies that we own. To curtail that speech violates our self-ownership, or in a phrase: my body, my speech.

Surely, it is possible that you believe falsely about this-or-that modal matter. In light of the various ways the world could be arranged, it is plausible thatthere is a nearby possible world, which would be almost identical to the actual world, if it were actualized, where you and your modal counterpart disagree over modal belief p. You might be tempted to think that your modal belief is true, while hers is not. It is not clear why this is so; after (...) all, you would each have the same evidence, cognitive abilities etc., if you were both actualized. This point generalizes to all of your modal beliefs, this seems to strongly imply that the probability that you have true modal beliefs appears inscrutable. Thus, you have some reason to withhold belief, on modal matters. (shrink)

El equipo multidisciplinario especializado, con ayudas diagnósticas avanzadas, brinda, en las unidades de cuidados intensivos neonatales, atención a los recién nacidos en estado crítico de salud. No comprender la muerte como un acontecimiento natural dificulta establecer un equilibrio en el tratamiento proporcionado y exige una juiciosa valoración de los beneficios y cargas basados en una ética responsable. La literatura sugiere que se necesita, en relación con los aspectos bioéticos de la práctica clínica, de capacitación, participación y presencia permanente de los (...) profesionales de la salud en la toma de decisiones en conjunto con las madres, de tal forma que se proporcione consuelo a la familia del neonato. (shrink)

I assess the debate over the Suicide Machine Argument. There are several lessons to be learned from this debate. First, there is a fruitful distinction to be made,between tensed and tenseless versions of presentism, despite the temptation to suppose that presentism is a tensed theory of time. Second, once we’ve made the distinction between different kinds of presentism, it is clear that Licon’s objection protects the tenseless version of presentism from the Suicide Machine Argument; however, the argument is still effective (...) against the tensed version. Finally, I argue that if the presentist wants to remain a card carrying presentist, in the face of the challenge posed by Hales, then she must abandon her commitment to tense. (shrink)

Se muestra como las tesis de la filosofía de la historia de Benjamin, permiten que pensemos la historia y la acción política en forma distinta a como han sido concebidas en la historiografía y la política tradicional. Así mismo, en contra de lo que podría sugerir una lectura inicial de la tesis, lo que Benjamin denomina como la acción política revolucionaria, necesitaría de una acción desligada de la violencia para poder romper con el continuo de la historia. Por último, señalamos (...) como los límites de pensar la política desvinculada de la noción del progreso histórico, permite que ésta pueda contribuir al reconocimiento de las víctimas y olvidados de la historia. (shrink)

There is a solid empirical evidence for moral mediocrity: people aim to be about as morally good, and as morally bad, as those around them. This can be good if most people are saints, and very bad if most people are moral monsters. And here we derive an important insight: we can have a just society without just citizens--that is, citizens who act just only from peer pressure, and not from moral reason--provided most people in that society, for whatever reason, (...) happen to act justly. Even though Kant wouldn't approve, the resulting society would be just. (shrink)

Este trabajo ha sido seleccionado de entre los participantes en la VI Olimpiada de Filosofía que organiza FICUM en la modalidad de secundaria y bachillerato, para promocionar la filosofía entre los jóvenes.

Con la promulgación de la Ley 30 de 1986, se incluyó el concepto del consumo de la dosis personal de drogas. La Corte Constitucional, mediante sentencia C-221 de 1994, resolvió la demanda de constitucionalidad presentada por el ciudadano Alexandre Sochandamandou, ratificando el concepto de “dosis personal de consumo de drogas”, y despenalizando el mismo. En este artículo se plantea el desconocimiento de la legislación y la jurisprudencia acerca de la opinión técnico-científica en cuanto a esta temática, que originó diversas inconveniencias, (...) inconsistencias, vacíos e imprecisiones técnico-científicas que riñen con normas y tratados internacionales de ética médica, al igual que con evidencia médica encontrada sobre los efectos adversos ocasionados por las drogas en la salud de los consumidores de estas sustancias. (shrink)

El ms. árabe num. 1.077 de El Escorial contiene una obra de Abū Isḥāq al-Garnāṭī, cuyo último capítulo lo constituye la enumeración de veintidós normas jurídicas, en cuatro de las cuales los andalusíes no siguieron la doctrina de Mālik, y en las dieciocho restantes se apartaron de la de Ibn al-Qāsim. Ese mismo texto aparece también al final de K. al-Mufīd del cordobés Ibn Hišām. En este artículo su autor, tras definir el concepto de ‛amal local, plantea la cuestión de (...) la autoría del citado texto, ofrece una edición crítica y traducción del mismo a partir de las dos fuentes mencionadas y hace un estudio diacrónico de la aplicación en al-Andalus de esas controvertidas normas. Dicho estudio muestra que tales diferencias con respecto a Mālik o Ibn al-Qāsim no siempre se mantuvieron, sino que caracterizaron más bien el fiqh «temprano» andalusí. (shrink)

En este artículo se examinan, en primer lugar, los desarrollos aristotélicos acerca del fenómeno del psitacismo (la repetición inútil de palabras y expresiones), tal y como son expuestos en las Refutaciones sofísticas. Estos análisis son utilizados, en segundo lugar, para aclarar un argumento propuesto en Metafísica B de acuerdo con el cual el ser no es un género.